The secondary
structure of Dihydrofolate Reductase is composed of alpha
helices and beta sheets
.
Secondary Structure: consists
of regularities in local conformation (folding or coiling) that are
primarily maintained by noncovalent hydrogen bonds between carbonyl
oygens and amide hydrogens of the
peptide bond.
- Alpha
Helices: maintained by hydrogen bonds between carbonyl oxygen
and hydrogen of amide that is part of the backbone
View Alpha Helix Structure
- Beta
Sheets: maintained by hydrogen bonds of carbonyl oxygen and
amide hydrogen of adjacent beta strands
View Beta Sheet Structure
Note: Images of Alpha Helix
and Beta Sheet Structures taken from web site http://www.uic.edu/classes/bios/bios100/lecturesf04am/lect02.htm